Human Tubular Cells

1201 Human Proximal Tubule Epithelial Cells – Adult (PTEC)

Cryopreserved ampules of Adult Human Proximal Tubule Epithelial Cells (PTEC) containing 500,000 – 1,000,000 cells (dependant on batch).

Our primary human PTEC are isolated from adult renal cortex and cultured to preserve function and phenotype. When cultured under our recommended culture conditions the PTEC retain many of the key functions observed in vivo. These include basolateral K-Cadherin expression, albumin-mediated endocytosis and SGLT expression.

1Eletron Micrograph of HSL PTEC
2 K-cadherin staining with TRITC counterstained with DAPI in HSL PTEC
Gamma GT staining in HSL Primary PTEC

For more information on quantities and prices please contact us: info@helierscientific.com

References

  1. Sharpe CC, Dockrell ME (2012) Primary Culture of Human Renal Proximal Tubule Epithelial Cells and Interstitial Fibroblasts. Methods Mol Biol.  Human Cell Culture Protocols 806:175-85
  1. Diwakar R et al (2007) The role played by endocytosis in albumin-induced secretion of TGF-beta1 by proximal tubular epithelial cells. Am J Physiol Renal Physiol.;292:F1464-70.
  1. Phanish MK et al (2015) The Regulation of TGFβ1 Induced Fibronectin EDA Exon Alternative Splicing in Human Renal PTEC. J Cell Physiol. 230:286-95.